Anthony Durkin
Biography
Anthony J. Durkin, Ph.D., is Associate Researcher in the Department of Biomedical Engineering and Director of the Spatial Frequency Domain Imaging Lab at the Beckman Laser Institute and Medical Clinic, University of California, Irvine. His research centers on the development and clinical translation of spatial frequency domain imaging (SFDI), a wide-field, non-contact near-infrared spectral imaging technique capable of quantitatively mapping tissue optical properties, oxygenation, and composition in vivo. He is a co-founder of Modulated Imaging, Inc. (now Modulim, Inc.), the company that has commercialized this technology, and holds fifteen issued U.S. patents including ones related to spatially structured illumination and wide-field functional imaging.
Durkin's work has been supported by the National Institutes of Health, the Air Force Office of Scientific Research, and the U.S. Army Combat Casualty Care Research Program, among other sponsors. His laboratory has applied SFDI extensively to burn wound severity assessment, reconstructive surgery, skin cancer, and organ viability monitoring. He is the principal investigator of an NIH NIGMS R01 focused on clinical evaluation of burns using SFDI, and serves as a co-investigator on projects addressing directed-energy-induced tissue damage and the SFDI to characterize the evolution of thyroid eye disease. His research has accumulated more than 11,000 citations, with an h-index of 59 (Sept 16, 2026).
Durkin is an elected Fellow of SPIE and a Senior Member of Optica (formerly the Optical Society of America). He serves as Senior Topical Editor for the SPIE Journal of Biomedical Optics and has been a member of its editorial board since 2003. He previously served as Co-Editor-in-Chief of the Virtual Journal of Biomedical Optics (2010–2016). Durkin received his Ph.D. in Biomedical Engineering from the University of Texas, Austin under the mentorship of Rebecca Richards-Kortum. He was an National Research Council Post-doc at the US Food & Drug Administration for 3 years. He worked as Director of Bioscience at Candela (medical laser company) in Wayland for 3 years, contributing to projects related to laser-based treatment for sleep apnea, laser reduction of acne, and optical imaging as a surrogate for Moh's surgery. He has been at the Beckman Laser Institute & Medical Clinic since Jan. 2001.
Return to topEducation
- Ph.D. in Biomedical Engineering, University of Texas, Austin
- M.S. in Condensed Matter Physics, University of North Texas
- B.S. in Physics, Lamar University
Distinctions
- SPIE Fellow, 2017
- Best Paper, SPIE Photonics West 2020 Therapeutics and Diagnostics in Urology Conference, 2020
- Arnold and Mabel Beckman Foundation Fellowship, Beckman Laser Institute and Medical Clinic, 2001-2003
- National Academy of Sciences/National Research Council Research Fellowship, Electro-Optics Branch/FDA, 1995-1997
- New Focus/Optical Society of America Student Travel Award, CLEO, 1992
- Senior Member, SPIE, 2016
- Senior Member, Optical Society of America, 2018
- 3rd Place Poster, Military Health System Research Symposium, 2023
- Gordon Research Council Post-Doc/Graduate Student Award, Conference on Lasers in Medicine and Biology, 1996
- Member, Sigma Pi Sigma, National Physics Honor Society, 1982-present
Areas of Expertise
- Biomedical Optics and Biophotonics
- Diffuse Optical Spectroscopy Tissue
- Fluorescence Spectroscopy Turbid Media
- Skin Chromophore Quantification
- Spatial Frequency Domain Imaging
- Burn Wound Severity Classification
- Short-Wave Infrared Tissue Imaging
Recent Publications
- Gordon T. Kennedy, Christopher A. Campbell, Alexis M. Fox, Robert J. Christy, Theresa Chin, Victor C. Joe, Anthony J. Durkin, “Spatial frequency domain assessment of burns in a clinical setting: a comparison of a research-grade and a commercial imager at the UCI Regional Burn Center” (opens in new tab), Progress in Biomedical Optics and Imaging Proceedings of SPIE, vol. 13823, 2026. Presented at SPIE Photonics West, Photonics in Dermatology and Plastic Surgery 2026, Moscone Center, San Francisco.
- Kennedy G.T., Rowland R., Mazhar A., Cuccia D.J., Durkin A.J., “Rapid Quantitative Imaging of Heterogeneous Tissue Hemoglobin Dynamics Using Spatial Frequency Domain Imaging” (opens in new tab), Journal of Vascular Research, pp. 1-10, 2026.
- Wilson R.H., Kennedy G.T., Campbell C.A., Phan T., Lin A.H., Levi B., Durkin A.J., “Short-wave infrared (SWIR) spectroscopy and imaging of biological tissues: a decade of advancements (2016-2025)” (opens in new tab), Journal of Biomedical Optics, vol. 31, 2026.
- Phan T., Campbell C.A., Kennedy G.T., Wakida N., Makeeva N., Tabone G., Chin T.L., Joe V.C., Choi B., Durkin A.J., “Two-step regression analysis approach to assess burn wound severity using spatial frequency domain imaging” (opens in new tab), Journal of Biomedical Optics, vol. 31, 2026.
- Jia W., Katta N., Kennedy G.T., Lee J., Nguyen E., Lai O., Jeong Y., Elsanadi R., Messele F., Johnson J.E., Stemmer-Rachamimov A.O., Nelson J.S., Sierra R., Kelly K.M., Durkin A.J., Milner T.E., “Optical and acoustic scattering in cutaneous neurofibromas: Implications for early detection” (opens in new tab), Journal of Investigative Dermatology, 2026.
- A. Martín-Pérez, C. Campbell, G.T. Kennedy, A.M. Fox, E. Juarez, C. Sanz, T. Chin, V. Joe, A.J. Durkin, “Enhancing burn wound classification with ensemble learning using spatial frequency domain imaging applied to in-vivo porcine skin” (opens in new tab), Progress in Biomedical Optics and Imaging Proceedings of SPIE, SPIE, vol. 13292, pp. 94-100, 2025. Presented at Photonics in Dermatology and Plastic Surgery 2025.
- C.A. Campbell, G.T. Kennedy, N. Wakida, R. Rowland, C. LaNguyen, A.M. Fox, T. Chin, V. Joe, A.J. Durkin, “Polarized microscopy with picrosirius red: potential for reproducible burn depth grading” (opens in new tab), Progress in Biomedical Optics and Imaging Proceedings of SPIE, SPIE, vol. 13292, pp. 101-106, 2025. Presented at Photonics in Dermatology and Plastic Surgery 2025.
- R.H. Wilson, R. Rowland, G.T. Kennedy, C. Campbell, V.C. Joe, T.L. Chin, D.M. Burmeister, R.J. Christy, A.J. Durkin, “Review of machine learning for optical imaging of burn wound severity assessment” (opens in new tab), Journal of Biomedical Optics, vol. 29, no. 2, pp. 020901, 2024.
- L.S. Ediriwickrema, S. Sung, K.C. Mattick, M.B. An, C. Malley, S.D. Kirk, D. Devineni, J.M. Lee, G.T. Kennedy, B. Choi, A.J. Durkin, “Multimodal optical imaging of the oculofacial region using a solid tissue-simulating facial phantom” (opens in new tab), Journal of Biomedical Optics, vol. 29, no. 8, pp. 086002-086002, 2024.
- T. Phan, C. Crouzet, G.T. Kennedy, A.J. Durkin, B. Choi, “Quantitative hemodynamic imaging: a method to correct the effects of optical properties on laser speckle imaging” (opens in new tab), Neurophotonics, vol. 10, no. 4, pp. 045001, 2023.
- Thinh Phan, Rebecca Rowland, Adrien Ponticorvo, Binh Cong Le, Seyed A. Sharif, Gordon T. Kennedy, Nicole Bernal, Robert H. Wilson, Anthony J. Durkin, “Quantifying the confounding effect of pigmentation on measured skin tissue optical properties: A comparison of colorimetry with Spatial Frequency Domain Imaging” (opens in new tab), Journal of Biomedical Optics, vol. 27, no. 3, pp. 036002, 2022.
- Thinh Phan, Rebecca Rowland, Adrien Ponticorvo, Binh C. Le, Robert H. Wilson, Seyed A. Sharif, Gordon T. Kennedy, Nicole Bernal, Anthony J. Durkin, “Characterizing reduced scattering coefficient of normal human skin across different anatomic locations and Fitzpatrick skin types using spatial frequency domain imaging” (opens in new tab), Journal of Biomedical Optics, vol. 26, no. 2, pp. 026001, 2021.
- Gordon T. Kennedy, Keiichiro Kagawa, Rebecca Rowland, Adrien Ponticorvo, Jun Tanida, Anthony J. Durkin, “A spatial frequency domain imager based on a compact multi-aperture camera: testing and feasibility for non-invasive burn severity assessment” (opens in new tab), Journal of Biomedical Optics, vol. 26, no. 8, pp. 086001, 2021.
Most Cited Publications
- D. J. Cuccia, F. Bevilacqua, A. J. Durkin, F. Ayers, B. J. Tromberg, “Quantitative Mapping of Turbid Media Optical Properties using Modulated Imaging” (opens in new tab), Journal of Biomedical Optics, vol. 14, pp. 024012, 2009.
- D.J. Cuccia, F. Bevilacqua, A.J. Durkin, B.J. Tromberg, “Modulated Imaging: Quantitative Analysis and Tomography of Turbid Media in the Spatial Frequency Domain” (opens in new tab), Optics Letters, vol. 30, no. 11, pp. 1354-1356, 2005.
- Lorenzo Brancaleon, Anthony J. Durkin, John H. Tu, Gregg Menaker, Jerome D. Fallon, Nikiforos Kollias, “In-vivo fluorescence spectroscopy of Non-Melanoma Skin Cancer” (opens in new tab), Photochemistry and Photobiology, vol. 73, no. 2, pp. 178-183, 2001.
- Sheng-Hao Tseng, Paulo Bargo, Anthony Durkin, Nikiforos Kollias, “Chromophore Concentrations, Absorption and Scattering Properties of Human Skin In-vivo” (opens in new tab), Optics Express, vol. 17, no. 17, pp. 14599-14617, 2009.
- Meghann Kaiser, Amr Yafi, Marianne Cinat, Bernard Choi, Anthony J Durkin, “Noninvasive Assessment of Burn Wound Severity Using Optical Technology: A Review of Current and Future Modalities” (opens in new tab), Burns, vol. 37, no. 3, pp. 377-86, 2011.
- Sheng-Hao Tseng, Alexander Grant, Anthony J. Durkin, “In-vivo Determination of Skin Optical Properties using Diffuse Optical Spectroscopy” (opens in new tab), Journal of Biomedical Optics, vol. 13, no. 1, pp. 014016, 2008.
- John Quan Minh Nguyen, Christian Crouzet, Tuan Mai, Kathleen Riola, Daniel Uchitel, Lih-Huei L Liaw, Nicole Bernal, Adrien Ponticorvo, Bernard Choi, Anthony J Durkin, “Spatial Frequency Domain Imaging of Burn Wounds in a Preclinical Model of Graded Burn Severity” (opens in new tab), Journal of Biomedical Optics, vol. 18, no. 6, pp. 66010, 2013.
- A.J. Durkin, S. Jaikumar, N. Ramanujam, R. Richards-Kortum, “Relation Between Fluorescence Spectra of Dilute and Turbid Samples” (opens in new tab), Applied Optics, vol. 33, no. 3, pp. 414-423, 1994.
- Adrien Ponticorvo, David M. Burmeister, B. Yang, Bernard Choi, Robert J. Christy, Anthony J. Durkin, “Quantitative assessment of graded burn wounds in a porcine model using Spatial Frequency Domain Imaging (SFDI) and Laser Speckle Imaging (LSI)” (opens in new tab), Biomedical Optics Express, vol. 5, no. 10, pp. 3467-3481, 2014.
- Tim A. Erickson, Amaan Mazhar, David Cuccia, Anthony Durkin, James W. Tunnell, “A Lookup-Table Method for Imaging Optical Properties with Structured Illumination Beyond the Diffusion Theory Regime” (opens in new tab), Journal of Biomedical Optics, vol. 15, pp. 036013, 2010.
Contact Information
Website: https://profiles.icts.uci.edu/anthony.durkin
Email: adurkin@uci.edu
Phone: (949)874-3637
Address: 1002 Health Sciences Rd East, Beckman Laser Institute and Medical Clinic, University of California Irvine, 92617
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Last updated on 9/16/2026.