Areg Grigorian
Biography
Areg Grigorian, M.D., FACS, is Assistant Clinical Professor of Surgery in the Division of Trauma and Surgical Critical Care at the University of California, Irvine. He received his M.D. from the University of California, San Diego in 2014, completed general surgery residency at the University of California, Irvine in 2020, and completed fellowships in Surgical Critical Care and AAST Acute Care Surgery at LAC+USC Medical Center in 2021 and 2022. Grigorian has focused his research on trauma and surgical critical care outcomes, with particular emphasis on clinical outcomes research examining injury patterns, treatment protocols, and disparities in trauma care. His work has resulted in over 250 peer-reviewed publications examining topics ranging from blunt cerebrovascular injury and antibiotic timing in open fractures to firearm violence and outcomes in special populations.
Grigorian serves as co-editor and chapter author for multiple surgical textbooks, including "Surgery: A Case Based Clinical Review" (three editions) and "Review of Surgery for ABSITE and Boards" (three editions). The first edition of "Surgery: A Case Based Clinical Review" has been accessed over 919,000 times and the second edition over 164,000 times, making it one of the top 10 Springer textbooks in healthcare and medicine. He has mentored over 40 medical students, residents, and research fellows in clinical outcomes research, with many projects resulting in peer-reviewed publications. Grigorian directs the Surgery Shelf Boot Camp for third-year medical students and serves as instructor and course director for multiple trauma education courses including ASSET, ATLS, and Stop the Bleed.
Grigorian is a Fellow of the American College of Surgeons and member of the American Association for the Surgery of Trauma, Southwestern Surgical Congress, Eastern Association for the Surgery of Trauma, and Pacific Coast Surgical Association. He serves as reviewer for ten surgical journals and was appointed Chair of the Committee on Applicants for District 6 of the American College of Surgeons in 2025. His honors include Outstanding Resident of the Year at UC Irvine in 2020, finalist for the American College of Surgeons Resident Award for Exemplary Teaching in 2019, and the Rising Star Award from UC Irvine in 2024.
Return to topEducation
- BA in Psychology, University of California, Berkeley, 2009
- MD in Medicine, University of California, San Diego, 2014
Distinctions
- Fellow of the American College of Surgeons (FACS)
- Best Research Paper Finalist, Karmody Research Competition, The Society for Clinical Vascular Surgery, 2018
- Finalist for American College of Surgeons Resident Award for Exemplary Teaching, 2019
- Chair, Committee on Applicants, District 6, American College of Surgeons, 2025
- Jack A. Barney Research Award Nomination, Southwestern Surgical Congress, 2019
- Best Resident Paper Competition Winner for Southern California Caucus, Pacific Coast Surgical Association, 2020
- Chief-Resident in charge of Surgical Education, University of California Irvine, 2020
- Outstanding Resident of the Year, University of California Irvine, 2020
- Medical Education Excellence in Teaching Award, University of California Irvine, 2020
- Fresh Tissue Dissection Lab (FTDL) Education Fellow, University of Southern California, 2021
Areas of Expertise
- Trauma and Surgical Critical Care
- Blunt Cerebrovascular Injury Management
- Venous Thromboembolism Prophylaxis
- Pediatric Trauma Outcomes
- Firearm Violence Epidemiology
- COVID-19 Pandemic Trauma Patterns
- Surgical Stabilization Rib Fractures
Recent Publications
- Painter R., Grigorian A., Sargent B., Liang T., Homo R., Conovaloff J., Schubl S., Kirby K., Jebbia M., Swentek L., Nahmias J., “Viscoelastic assay versus conventional coagulation-directed resuscitation for severely injured trauma patients undergoing massive transfusion” (opens in new tab), Surgery United States, vol. 190, 2026.
- Nie J., Grigorian A., Aryan N., Truong N., Kuza C., Burrus S., Nahmias J., “Comparative Analysis of Profiles and Outcomes for Elderly Patients with or without Reported Abuse” (opens in new tab), American Surgeon, vol. 92, pp. 231-237, 2026.
- Aryan N., Grigorian A., Nahmias J., Dolich M., Lekawa M., Nie J., Schubl S.D., “Impact of obesity on outcomes of surgical stabilization of rib fractures” (opens in new tab), Journal of Trauma and Acute Care Surgery, vol. 100, pp. 54-59, 2026.
- Hegazi M, Nahmias J, Lekawa M, Dolich M, Kong A, Barrios C, Grigorian A, “Risk factors and timing of fasciotomy for isolated pediatric lower extremity trauma” (opens in new tab), American Surgeon, vol. 91, pp. 998-1005, 2025.
- Avinash F., Nahmias J., Aryan N., Jeng J., Barrios C., Nguyen P.D., Grigorian A., “Predictors of ventilator-associated pneumonia in intubated pediatric trauma patients” (opens in new tab), Pediatric Surgery International, vol. 41, 2025.
- Nguyen P., Grigorian A., Nahmias J., Aryan N., Jebbia M., Burruss S., Chin T.L., Swentek L., “Higher Rates of Traumatic Brain Injury in Blunt Trauma Patients With Cirrhosis: Worse Outcomes With Concomitant Alcohol Use Disorder” (opens in new tab), American Surgeon, vol. 91, pp. 2039-2048, 2025.
- Martino A.M., Grigorian A., Kuza C.M., Burruss S., Swentek L., Guner Y., Goodman L.F., Nahmias J., “Comparison of cervical versus thoracic spinal cord injury outcomes in pediatric trauma patients” (opens in new tab), Pediatric Surgery International, vol. 41, 2025.
- Painter R., Nahmias J., Nguyen P.D., Guner Y., Goodman L.F., Chen P.M., Chen J., Liang T., Grigorian A., “Whole blood transfusion in pediatric trauma patients with traumatic brain injury may decrease the risk of early death” (opens in new tab), Pediatric Surgery International, vol. 41, 2025.
- Khurana S., Bhullar A., Burger S., Grigorian A., Nahmias J., “Attitudes and practices surrounding primary care firearm safety counseling before and after a single pragmatic mixed-methods education session” (opens in new tab), Surgery United States, vol. 187, 2025.
- Nahmias J., Stopenski S., Jebbia M., Atallah S., Kirby K.A., Alvarez C.A., Aryan N., Tay-Lasso E., Dolich M., Lekawa M., Swentek L., Santos J., Schubl S., Kuza C., Nguyen N., Grigorian A., “Dexmedetomidine for Analgesia in Nonintubated Patients with Traumatic Rib Fractures: A Randomized Clinical Trial” (opens in new tab), JAMA Surgery, vol. 160, pp. 1047-1056, 2025.
- Hunter D., Nahmias J., Aryan N., Dolich M., Swentek L., Bagga A., Grigorian A., “The Hidden Toll: Demographic Changes in Suicide Attempts During the Coronavirus Disease-19 Era” (opens in new tab), Journal of Surgical Research, vol. 313, pp. 509-515, 2025.
- Nguyen L., Grigorian A., Lee C., Goodman L.F., Guner Y., Kuza C., Swentek L., Nahmias J., “Similar Associated Risk of Complication and Death for Adolescent Gunshot Wounds Treated at Pediatric-Only Hospitals When Compared with Combined Pediatric and Adult Centers” (opens in new tab), Journal of the American College of Surgeons, vol. 241, pp. 232-238, 2025.
- Sedighim S., Grigorian A., Kuza C.M., Swentek L., Burruss S., Inaba K., Goodman L.F., Nahmias J., “Comparing Admission Patterns Between Combined Pediatric–Adult and Pediatric-Only Trauma Centers” (opens in new tab), Journal of Surgical Research, vol. 312, pp. 1-6, 2025.
- Lee C., Grigorian A., Rutledge R., Dolich M., Lekawa M.E., Aryan N., Barrios C., Nahmias J., “Increased Associated Risk of Surgical Site Infections in Trauma Patients Who Are Smokers” (opens in new tab), Journal of Surgical Research, vol. 312, pp. 221-226, 2025.
- Park F.S., Nahmias J., Shin J., Li J.Y., Barrios C., Schubl S., Grigorian A., “Trauma, firearms, and pregnancy: Beyond the cushion” (opens in new tab), Surgery Open Science, vol. 26, pp. 22-26, 2025.
- Epstein L., Nahmias J., Schubl S., Inaba K., Matsushima K., Lekawa M., Dolich M., Grigorian A., “Emergency Department Placed Central Lines for Trauma Patients: A Retrospective Case-Control Study on Central Line–Associated Blood Stream Infection Risk From Central Lines Placed Emergently in the Emergency Department” (opens in new tab), Jacep Open, vol. 6, 2025.
- Sharma V., Grigorian A., Burruss S., Swentek L., Scolaro J., Jebbia M., Kuza C.M., Nahmias J., “Incidence and Predictors of Hollow Viscus Injury in Patients With Abdominal Morel-Lavalleé Injury” (opens in new tab), Journal of Surgical Research, vol. 308, pp. 307-314, 2025.
- Jebbia M., Nahmias J., Schubl S., Dolich M., Lekawa M., Kong A., Grigorian A., “Propensity matched analysis of DPA or DPL used within the first hour for severely hypotensive blunt trauma patients” (opens in new tab), Surgery Open Science, vol. 24, pp. 1-4, 2025.
- Rakhit S., Grigorian A., Rivera E.L., Alvarado F.A., Patel M.B., Maiga A.W., “Plasma transfusion and hospital mortality in moderate-severe traumatic brain injury” (opens in new tab), Injury, vol. 56, 2025.
- Clark I., Nahmias J., Jebbia M., Aryan N., Lucas A.N., Fierro N., Dhillon N.K., Ley E.J., Smith J., Burruss S., Dahan A., Johnson A., Ganske W., Biffl W.L., Bayat D., Castelo M., Wintz D., Schaffer K.B., Zheng D.J., Tillou A., et al., “Incidence and Outcomes of Pregnant Trauma Patients With Positive Urine Toxicology: A Southern California Multicenter Study” (opens in new tab), American Surgeon, vol. 91, pp. 259-265, 2025.
Most Cited Publications
- Yeates EO, Grigorian A, Barrios C, Schellenberg M, Owattanapanich N, Barmparas G, Margulies D, Juillard C, Garber K, Cryer H, Tillou A, Burruss S, Penaloza-Villalobos L, Lin A, Figueras RA, Brenner M, Firek C, Costantini T, Santorelli J, Curry T, et al., “Changes in traumatic mechanisms of injury in Southern California related to COVID-19: Penetrating trauma as a second pandemic.” (opens in new tab), Journal of Trauma and Acute Care Surgery, vol. 90, no. 4, pp. 714-721, 2021.
- Donnelly MR, Grigorian A, Swentek L, Arora J, Kuza CM, Inaba K, Kim D, Lekawa M, Nahmias J, “Firearm violence against children in the United States: Trends in the wake of the COVID-19 pandemic.” (opens in new tab), Journal of Trauma and Acute Care Surgery, vol. 92, no. 1, pp. 65-68, 2022.
- Grigorian A., Spencer D., Donayre C., Nahmias J., Schubl S., Gabriel V., Barrios C., “National Trends of Thoracic Endovascular Aortic Repair Versus Open Repair in Blunt Thoracic Aortic Injury” (opens in new tab), Annals of Vascular Surgery, vol. 52, pp. 72-78, 2018.
- Grigorian A., Kabutey N.-K., Schubl S., de Virgilio C., Joe V., Dolich M., Elfenbein D., Nahmias J., “Blunt cerebrovascular injury incidence, stroke-rate, and mortality with the expanded Denver criteria” (opens in new tab), Surgery United States, vol. 164, pp. 494-499, 2018.
- Donnelly MR, Grigorian A, Inaba K, Kuza CM, Kim D, Dolich M, Lekawa M, Nahmias J, “A Dual Pandemic: The Influence of Coronavirus Disease 2019 on Trends and Types of Firearm Violence in California, Ohio, and the United States” (opens in new tab), Journal of Surgical Research, vol. 263, pp. 24-33, 2021.
- Hasjim BJ, Grigorian A, Barrios C Jr, Schubl S, Nahmias J, Gabriel V, Spencer D, Donayre C, “National Trends of Thoracic Endovascular Aortic Repair versus Open Thoracic Aortic Repair in Pediatric Blunt Thoracic Aortic Injury.” (opens in new tab), Annals of Vascular Surgery, vol. 59, pp. 150-157, 2019.
- Grigorian A., Livingston J.K., Schubl S.D., Hasjim B.J., Mayers D., Kuncir E., Barrios C., Joe V., Nahmias J., “National analysis of testicular and scrotal trauma in the USA” (opens in new tab), Research and Reports in Urology, vol. 10, pp. 51-56, 2018.
- Livingston JK, Grigorian A, Kuza CM, Lekawa M, Bernal N, Allen A, Nahmias J, “Non-accidental trauma increases length of stay and mortality in pediatric trauma.” (opens in new tab), Pediatric Surgery International, vol. 35, no. 7, pp. 779-784, 2019.
- Dosch AR, Grigorian A, Delaplain PT, Bartholomew TS, Won EJ, Gabriel V, Wolf RF, Jutric Z, Imagawa DK, “Perioperative blood transfusion is associated with an increased risk for post-surgical infection following pancreaticoduodenectomy.” (opens in new tab), HPB (Oxford), vol. 21, no. 11, pp. 1577-1584, 2019.
- Grigorian A., Sugimoto M., Joe V., Schubl S., Lekawa M., Dolich M., Kuncir E., Barrios C., Nahmias J., “Pressure Ulcer in Trauma Patients: A Higher Spinal Cord Injury Level Leads to Higher Risk” (opens in new tab), Journal of the American College of Clinical Wound Specialists, vol. 9, pp. 24-31.e1, 2017.
Contact Information
Email: agrigori@uci.edu
Address: 3200 Chapman, Ste 6200, Irvine, CA 92697
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Last updated on 2/17/2026.