Andrew Reed Reikes
Biography
Andrew Reed Reikes, M.D., F.A.C.E., is Health Sciences Clinical Professor and Vice Chair for Ambulatory Clinical Operations in the Department of Medicine at the University of California, Irvine, where he also serves as Chief of the Division of General Internal Medicine. He received his M.D. from the University of California, San Diego, and completed his fellowship in Endocrinology, Diabetes, and Metabolism at UC Irvine. Reikes has held numerous administrative positions at UC Irvine, including Associate Dean for Primary Care, Medical Director for Primary Care and Multispecialty Services, and Network Medical Director for Utilization Management Services. He serves as a co-investigator on multiple NIH-funded research projects, including the All of Us research program and studies examining diabetes management, electronic health records interventions, and dietary effects on glycemic control.
Reikes has been elected Fellow of the American College of Endocrinology and currently serves as Chair of the Professional Standards Committee and Clinical Practice Guideline Subcommittee for the American Association of Clinical Endocrinologists/American College of Endocrinology, a position he has held since 2022. He previously served as Vice Chair of this committee from 2018 to 2022. He has been a member of multiple disease state networks within the organization, including thyroid disease, diabetes, and lipids and cardiovascular disease. Reikes has served as a manuscript reviewer for the Journal of General Internal Medicine and the Journal of Endourology, and previously served on the American Board of Internal Medicine as a relevance reviewer and question developer for the Endocrinology subspecialty division.
Reikes has received multiple Excellence in Teaching awards from UC Irvine School of Medicine, voted on by medical students in 2007, 2008, 2009, 2010, 2012, 2018, and 2019. He has delivered over 300 invited presentations on endocrine topics to medical students, residents, fellows, and practicing physicians throughout California. His clinical practice focuses on endocrinology, diabetes, and metabolism, and he has been involved in teaching medical students and residents at UC Irvine since 1996. He is board certified in Internal Medicine and Endocrinology, Diabetes, and Metabolism.
Return to topEducation
- B.S. in Psychobiology, University of California, Los Angeles, 1985
- M.D., University of California, San Diego, 1989
Distinctions
- Fellow, American College of Endocrinology, 1999
- Excellence in Teaching Award, UC Irvine School of Medicine, 2007-2010, 2012, 2017-2018
- Patient Experience Award, Top 20 Doctor in patient communications, UC Irvine Health, 2019
- Top Doctor for Outstanding Performance in physician communications skills, UC Irvine Medical Center and UC Irvine Health, 2020
- Guest Lecturer of the Year, UC Irvine Family Medicine Nurse Practitioner Program, 2008
- Outstanding Attending Teaching Award, Department of Medicine, 1998
- ARISE Award for Excellence, UC Irvine Medical Center, 2004
Areas of Expertise
- Endocrinology and Metabolism
- Type 2 Diabetes Management
- Thyroid Nodular Disease
- Osteoporosis Treatment
- Precision Medicine Cohort Enrollment
- Artificial Sweetener Glycemic Effects
- Electronic Health Record Optimization
Recent Publications
- Odegaard A.O., Chang J., Jiang L., Rashid S., Rydell S., Mitchell N.R., Bantle A.E., Seaquist E., Reikes A., Pereira M.A., “The Effect of Substituting Water for Artificially Sweetened Beverages on Glycemic and Weight Measures in People With Type 2 Diabetes: The Study of Drinks With Artificial Sweeteners (SODAS), a Randomized Trial” (opens in new tab), Diabetes Care, vol. 49, pp. 239-246, 2026.
- Hou, W., Tuttle, K.R., Reikes, A., Shen, W., Watanabe, J.H., “Trends in Pharmacological Treatment of Patients with New Onset Type 2 Diabetes: Usage Patterns in an Evolving Guideline Landscape” (opens in new tab), Journal of Diabetes, vol. 17, 2025.
- Hu, D., Guo, Y., Cho, H.N., Chow, E., Mukamel, D.B., Sorkin, D., Reikes, A., Perret, D., Pandita, D., Zheng, K., “When AI writes back: ethical considerations by physicians on AI-drafted patient message replies”, 2025. Presented at 2025 World Congress on Medical and Health Informatics (MedInfo '25), Taipei, Taiwan, August 2025.
- Watanabe J.H., Strand M.W., Shen W., Kwon J., Reikes A., “Insulin Glargine Utilization and Spending Before and After the First Biosimilar Insulin Glargine: A Real-World Data Study” (opens in new tab), Journal of General Internal Medicine, 2025.
- Mai Z., Kornak J., Dufault S.M., Strand M.W., Reikes A.R., Watanabe J.H., “Association of Baseline Comorbidities With First-Year Adherence to GLP-1 Receptor Agonists in Patients With Diabetes or Obesity: A Retrospective Cohort Study” (opens in new tab), Annals of Pharmacotherapy, 2025.
- Hasan, N., Chow, E., Yang, D., Iyer, P., Reikes, A., “Isolated Alkaline Phosphatase Elevation in Severe Osteoporosis Treatment: Implications of Teriparatide” (opens in new tab), Journal of Community Hospital Internal Medicine Perspectives, vol. 14, no. 6, 2024.
- Do, T., Chiao, E., Reikes, A., “A Case of Iatrogenic Cushing's Syndrome and Secondary Adrenal Insufficiency Due to Repeated Glucocorticoid Injections in the Ankle”, 2024. Presented at Society of General Internal Medicine California/Hawaii Regional Meeting, San Francisco, CA, January 2024.
- Odegaard, A., Chang, J., Jiang, L., Rashid, S., Rydell, S., Mitchell, N., Bantle, A., Seaquist, E., Reikes, A., Pereira, M., “The effect of substituting water for diet beverages on blood pressure and blood lipids in people with type 2 diabetes- The Study of Drinks with Artificial Sweeteners (SODAS)”, 2024. Presented at American Society of Nutrition Annual Meeting, Chicago, IL, July 2024.
- Watanabe, J.H., Kwon, J., Nan, B., Reikes, A., “Trends in Glucagon-like Peptide Receptor Agonist Use, 2014-2022” (opens in new tab), Journal of the American Pharmacists Association, vol. 64, pp. 133-138, 2023.
- Odegaard, A., Chang, J., Jiang, L., Rashid, S., Rydell, S., Mitchell, N., Bantle, A., Seaquist, E., Reikes, A., Pereira, M., “The effect of substituting water for diet beverages on CGM Metrics in People with Type 2 Diabetes- The Study of Drinks with Artificial Sweeteners (SODAS)”, 2023. Presented at American Diabetes Association Scientific Sessions, San Diego, CA, June 2023.
- Odegaard, A., Chang, J., Jiang, L., Rashid, S., Rydell, S., Mitchell, N., Bantle, A., Seaquist, E., Reikes, A., Pereira, M., “The effect of substituting water for diet beverages on overall diet quality measures in People with Type 2 Diabetes- The Study of Drinks with Artificial Sweeteners (SODAS)”, 2023. Presented at American Society of Nutrition Annual Meeting, Boston, MA, July 2023.
- Hasan, N., Chow, E., Reikes, A., Iyer, P., “An Unusual Rise in Alkaline Phosphatase”, 2023. Presented at American College of Physicians Southern California Region Meeting, Los Angeles, CA, October 2023.
- Reikes, A.R., Greb, A., Thakkar, A., “A Case of Mild Autonomous Cortisol Secretion Managed with Active Surveillance”, 2022. Presented at Endocrine Society Meeting, Atlanta, GA, June 2022.
- Reikes, A.R., Greb, A., “Efficacy of Treatment with PARP Inhibitor and Immunotherapy for Aggressive Adrenocortical Carcinoma with Cushing's Syndrome Refractory to Treatment with EDP Chemotherapy and Mitotane”, Journal of the Endocrine Society, no. April-May, 2021.
- Jones, N. M., Mukamel, D. B., Malik, S., Greenfield, R. S., Reikes, A., Wong, N. D., Chow, E., “The costs outweigh the benefits: Seeing side-effects online may decrease adherence to statins” (opens in new tab), BMC Medical Informatics and Decision Making, vol. 20, pp. 1-11, 2020.
- Reikes, A.R., Desai, R., “Management of VHL-associated pheochromocytoma in pregnancy”, Journal of the Endocrine Society, vol. 4, no. supplement 1, 2020.
- Sorkin, D.H., Billimek, J., August, K.J., Ngo-Metzger, Q., Kaplan, S.H., Reikes, A.R., Greenfield, S., “Mental health symptoms and patient-reported diabetes symptom burden: implications for medication regimen changes” (opens in new tab), Family Practice, vol. 32, no. 3, pp. 317-322, 2015.
- Tong, M.J., El-Farra, N.S., Reikes, A.R., Co, R.L., “Clinical outcomes after transfusion-associated hepatitis C” (opens in new tab), New England Journal of Medicine, vol. 332, no. 22, pp. 1463-1466, 1995.
Contact Information
Email: arreikes@uci.edu
Phone: (714) 456-7002
Address: Irvine, Zot 6250, Irvine, CA 92697-6250
Return to topThis profile was created with the help of AI.
Last updated on 3/11/2026.