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Bryan B. Shapiro

Bryan B. Shapiro

•Assistant Clinical Professor, Department of Psychiatry and Human Behavior, UC Irvine Medical Center
•Director of Psychopharmacology, UCI/UCD Train New Trainers (TNT) Primary Care Psychiatry Fellowship

Biography

Bryan B. Shapiro, M.D., M.P.H., is Assistant Clinical Professor in the Department of Psychiatry and Human Behavior at UC Irvine Medical Center. He received his medical degree from The Medical School for International Health in collaboration with Columbia University Medical Center and completed his psychiatry residency at UC Irvine Medical Center. Shapiro serves as Director of Psychopharmacology for the UCI/UCD Train New Trainers Primary Care Psychiatry Fellowship and Director of Psychiatry eConsults at UC Irvine Medical Center.

Shapiro's work focuses on psychopharmacology and the safe discontinuation of psychiatric medications. He is an Associate of the International Institute for Psychiatric Drug Withdrawal and serves as an Advisor to the U.S. Psychotropic Deprescribing Council. His research on antidepressant withdrawal has been featured in National Geographic and the American Psychiatric Association Medical Mind Podcast. He has published extensively on psychiatric medication management, including work examining serotonin transporter occupancy at subtherapeutic doses of antidepressants and establishing core symptoms of acute serotonin reuptake inhibitor withdrawal through international surveys.

Shapiro is the author of "The Psychopharmacology Blue Book: Outpatient Practice Companion" and has contributed chapters to "The Maudsley Deprescribing Guidelines" and the "Primary Care Psychiatry Textbook." He teaches advanced psychopharmacology to psychiatry residents and primary care psychiatry fellows at UC Irvine and serves as a senior consultant for Outro Health, Inc. Prior to his psychiatric training, Shapiro conducted research in nephrology and hemodialysis at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center.

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Education

  • B.A. in Neuroscience, Pomona College, 2011
  • M.P.H. in Public Health, UCLA Fielding School of Public Health, 2012
  • M.D., The Medical School for International Health in collaboration with Columbia University Medical Center, 2017
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Distinctions

  • National Chess Master, United States Chess Federation, 2020
  • Board Certification, American Board of Psychiatry and Neurology, 2021
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Areas of Expertise

  • Clinical Psychopharmacology
  • Hemodialysis Patient Physical Activity
  • Dialysis Mortality Predictors
  • Nutritional Assessment Methodology
  • Antidepressant Discontinuation Protocols
  • Serotonin Transporter Occupancy
  • Psychiatric Drug Withdrawal Symptoms

Recent Publications

  • “The Psychopharmacology Blue Book: Outpatient Practice Companion”, Wolters Kluwer, 2025.
  • Shapiro BB, Cohrs D, “Fluoxetine substitution for deprescribing antidepressants: a technical approach”, Journal of Psychiatry and Neuroscience, 2025.
  • Shapiro BB, Cohrs D, “Barriers to Safely Discontinuing Duloxetine: An Urgent Call to Action”, CNS Drugs, 2025.
  • Shapiro BB, Kramer E, Khoury D, Preda A, “Establishing core symptoms of acute serotonin reuptake inhibitor withdrawal: Results from an international survey of online peer-support communities”, Pharmacopsychiatry, 2023.
  • McCarron R, Shapiro BB, Rawles J, Luo J, “Depression (In the Clinic)” (opens in new tab), Annals of Internal Medicine, 2021.
  • Epstein D, Papoutsaki A, Shapiro BB, Jo E, “Understanding delivery of collectively built protocols in online health communities for discontinuation of psychiatric drugs”, Proceedings of the ACM on Human-Computer Interaction, vol. 5, no. CSCW2, pp. 1-29, 2021.
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Contact Information

Email: bryan.shapiro@uci.edu

Address: 3800 W. Chapman Ave. Orange, CA 92868, Irvine, CA 92697

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This profile was created with the help of AI.

Last updated on 3/11/2026.