David Buchbinder
Biography
David Buchbinder, M.D., M.S.H.S., is HS Associate Clinical Professor in the Department of Pediatrics at the University of California at Irvine and an Attending Physician in the Division of Hematology at Children's Hospital of Orange County, where he has served since 2009. He is also a member of the Population Sciences and Prevention Research Program at the UC Irvine Chao Family Comprehensive Cancer Center. Buchbinder received his Doctor of Medicine from the Medical College of Wisconsin and completed his fellowship in Pediatric Hematology and Oncology at Mattel Children's Hospital at UCLA, where he also earned a Master's of Science in Health Services from the UCLA School of Public Health.
Buchbinder's research focuses on psychosocial outcomes of siblings of childhood cancer survivors and late effects in hematopoietic cell transplant recipients. He has received multiple research awards including an ASCO Career Development Award (2011-2014) and served as an ASH Clinical Research Training Institute Scholar (2011-2012). His work has examined cancer prevention and screening practices, tobacco use, and quality of life among siblings of childhood cancer survivors through the Childhood Cancer Survivor Study, as well as late complications in patients undergoing transplantation for both malignant and non-malignant conditions.
Buchbinder serves as Founding Chair and Past Chair of the Clinical Immunology Special Interest Group for the American Society of Pediatric Hematology/Oncology and as Co-chair of the Late Effect and Quality of Life Working Committee for the Center for International Blood and Marrow Transplant Research. He has authored over 90 peer-reviewed publications on topics including primary immunodeficiency disorders, hematopoietic stem cell transplantation for non-malignant disorders, and psychosocial outcomes in pediatric oncology populations.
Return to topEducation
- B.A. in Mathematics - Applied, University of California at San Diego, 1999
- M.D., Medical College of Wisconsin, 2003
- M.S.H.S. in Health Services, UCLA School of Public Health, 2009
Distinctions
- ASCO Young Investigator Award, 2009-2010
- ASCO Career Development Award, 2011-2014
- ASH Clinical Research Training Institute Scholar, 2011-2012
- Clinical Immunology Society Summer School Selected Participant, 2012
- Jonsson Cancer Center Foundation Postdoctoral Fellowship Award, 2007-2008
- Standing Ovation Award, Medical College of Wisconsin Student Assembly, 2003
- Alice Litman Moss Annual Resident Award, 2006
- Stein Oppenheimer Endowment Award, 2009
- Alpha Omega Alpha, 2003
- Phi Beta Kappa, 1999
Areas of Expertise
- Pediatric Hematology Oncology
- Sibling Psychosocial Outcomes
- Primary Immunodeficiency Disorders
- Late Effects After Transplantation
- RAG Deficiency Autoimmunity
- Wiskott-Aldrich Syndrome Management
Recent Publications
- Sharma P., George N., Srivastava D., Chow E.J., Alderfer M.A., Leisenring W., Long K.A., Lown A.E., Oeffinger K.C., Zeltzer L.K., Armstrong G.T., Krull K.R., Brinkman T.M., Buchbinder D., “Psychosocial Health and Chronic Health Conditions Among Bereaved Siblings: A Report From the Childhood Cancer Survivor Study (CCSS)” (opens in new tab), Pediatric Blood and Cancer, vol. 72, 2025.
- Buchbinder D, Bhatt NS, Wang H, Yasui Y, Armenian S, Bhatia S, Chow EJ, Huang IC, Kirchoff AC, Leisenring W, Park ER, Yabroff KR, Armstrong GT, Nathan PC, Khera N, “Financial Hardship in Childhood Cancer Survivors Treated with Hematopoietic Cell Transplantation: A Report from the Childhood Cancer Survivor Study” (opens in new tab), Transplantation and Cellular Therapy, vol. 29, no. 11, pp. 705.e1-705.e9, 2023.
- Buchbinder D., Hsieh L., Frediani J., Zadeh N., Nael A., “MDS and MIRAGE” (opens in new tab), Journal of Pediatric Hematology Oncology, vol. 44, pp. 421-422, 2022.
- Buchbinder D., Chandrakasan S., “Hematopoietic Cell Transplantation” (opens in new tab), Tietz Textbook of Laboratory Medicine Seventh Edition, pp. 1316-1316.e23, 2022.
- Morales S., Salehabadi S.M., Srivastava D., Gibson T.M., Leisenring W.M., Alderfer M.A., Lown E.A., Zeltzer L.K., Armstrong G.T., Krull K.R., Buchbinder D., “Health-related and cancer risk concerns among siblings of childhood cancer survivors: a report from the Childhood Cancer Survivor Study (CCSS)” (opens in new tab), Journal of Cancer Survivorship, vol. 16, pp. 624-637, 2022.
- Lozano Chinga M.M., Buchbinder D., Walter J.E., “HistocompatIbility Antigens (HLA) and Transplantation” (opens in new tab), Absolute Allergy and Immunology Board Review, pp. 21-42, 2022.
- Buchbinder D., Khera N., “Psychosocial and financial issues after hematopoietic cell transplantation” (opens in new tab), Hematology United States, vol. 2021, pp. 570-577, 2021.
- Buchbinder D., Walter J.E., Butte M.J., Chan W.-Y., Chitty Lopez M., Dimitriades V.R., Dorsey M.J., Nugent D.J., Puck J.M., Singh J., Collins C.A., “When Screening for Severe Combined Immunodeficiency (SCID) with T Cell Receptor Excision Circles Is Not SCID: a Case-Based Review” (opens in new tab), Journal of Clinical Immunology, vol. 41, pp. 294-302, 2021.
- Buchbinder D., Scherwath A., “Neurocognitive dysfunction” (opens in new tab), Blood and Marrow Transplantation Long Term Management Survivorship After Transplant Second Edition, pp. 312-329, 2021.
- Buchbinder D.K., Singh J., Dao T., Sassoon A., Arrieta A., “Case Report: Pseudomonas can take a toll on a patient” (opens in new tab), F1000research, vol. 10, 2021.
Most Cited Publications
- Buchbinder D, Nugent DJ, Filipovich AH, “Wiskott-Aldrich syndrome: diagnosis, current management, and emerging treatments” (opens in new tab), Application of Clinical Genetics, vol. 7, pp. 55-66, 2014.
- Buchbinder D, Kelly DL, Duarte RF, Auletta JJ, Bhatt N, Byrne M, DeFilipp Z, Gabriel M, Mahindra A, Norkin M, Schoemans H, Shah AJ, Ahmed I, Atsuta Y, Basak GW, Beattie S, Bhella S, Bredeson C, Bunin N, Dalal J, et al., “Neurocognitive dysfunction in hematopoietic cell transplant recipients: expert review from the late effects and Quality of Life Working Committee of the CIBMTR and complications and Quality of Life Working Party of the EBMT” (opens in new tab), Bone Marrow Transplantation, vol. 53, no. 5, pp. 535-555, 2018.
- Buchbinder D, Hauck F, Albert MH, Rack A, Bakhtiar S, Shcherbina A, Deripapa E, Sullivan KE, Perelygina L, Eloit M, Neven B, Pérot P, Moshous D, Suarez F, Bodemer C, Bonilla FA, Vaz LE, Krol AL, Klein C, Seppanen M, et al., “Rubella Virus-Associated Cutaneous Granulomatous Disease: a Unique Complication in Immune-Deficient Patients, Not Limited to DNA Repair Disorders” (opens in new tab), Journal of Clinical Immunology, vol. 39, no. 1, pp. 81-89, 2019.
- Buchbinder D, Baker R, Lee YN, Ravell J, Zhang Y, McElwee J, Nugent D, Coonrod EM, Durtschi JD, Augustine NH, Voelkerding KV, Csomos K, Rosen L, Browne S, Walter JE, Notarangelo LD, Hill HR, Kumánovics A, “Identification of Patients with RAG Mutations Previously Diagnosed with Common Variable Immunodeficiency Disorders” (opens in new tab), Journal of Clinical Immunology, vol. 35, no. 2, pp. 119-24, 2015.
- Buchbinder D, Casillas J, Krull KR, Goodman P, Leisenring W, Recklitis C, Alderfer MA, Robison LL, Armstrong GT, Kunin-Batson A, Stuber M, Zeltzer LK, “Psychological Outcomes of Siblings of Cancer Survivors: A Report from the Childhood Cancer Survivor Study” (opens in new tab), Psycho Oncology, vol. 20, no. 12, pp. 1259-68, 2011.
- Kelly DL, Buchbinder D, Duarte RF, Auletta JJ, Bhatt N, Byrne M, DeFilipp Z, Gabriel M, Mahindra A, Norkin M, Schoemans H, Shah AJ, Ahmed I, Atsuta Y, Basak GW, Beattie S, Bhella S, Bredeson C, Bunin N, Dalal J, et al., “Neurocognitive Dysfunction in Hematopoietic Cell Transplant Recipients: Expert Review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and Complications and Quality of Life Working Party of the European Society for Blood and Marrow Transplantation” (opens in new tab), Biology of Blood and Marrow Transplantation, vol. 24, no. 2, pp. 228-241, 2018.
- Buchbinder D, Stinson JR, Nugent DJ, Heurtier L, Suarez F, Sukumar G, Dalgard CL, Masson C, Parisot M, Zhang Y, Matthews HF, Su HC, Durandy A, Fischer A, Kracker S, Snow AL, “Mild B-cell lymphocytosis in patients with a CARD11 C49Y mutation” (opens in new tab), Journal of Allergy and Clinical Immunology, vol. 136, no. 3, pp. 819-821, 2015.
- Buchbinder D, Nugent DJ, Brazauskas R, Wang Z, “Late Effects in Hematopoietic Cell Transplant Recipients with Acquired Severe Aplastic Anemia: A Report from the Late Effects Working Committee of the Center for International Blood and Marrow Transplant Research” (opens in new tab), Biology of Blood and Marrow Transplantation, vol. 18, no. 12, pp. 1776-84, 2012.
- Chandrakasan S, Chandra S, Davila Saldana BJ, Torgerson TR, Buchbinder D, “Primary immune regulatory disorders for the pediatric hematologist and oncologist: A case-based review” (opens in new tab), Pediatric Blood and Cancer, vol. 66, no. 5, pp. e27619, 2019.
- Perelygina L, Buchbinder D, Dorsey MJ, Eloit M, Hauck F, Hautala T, Moshous D, Uriarte I, Deripapa E, Icenogle J, Sullivan KE, “Outcomes for Nitazoxanide Treatment in a Case Series of Patients with Primary Immunodeficiencies and Rubella Virus-Associated Granuloma” (opens in new tab), Journal of Clinical Immunology, vol. 39, no. 1, pp. 112-117, 2019.
Contact Information
Email: dbuchbin@uci.edu
Phone: (714) 509-8459
Address: 1201 W. LaVeta Ave.
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Last updated on 4/27/2026.