Deepti Upparapalli
Biography
Deepti Upparapalli, M.D., is Assistant Clinical Professor in the Division of Cardiology at the University of California, Irvine. She received her Doctor of Medicine from American University of the Caribbean and completed fellowship training in Cardiovascular Disease at Christiana Care Health System affiliated with Sidney Kimmel Medical College at Thomas Jefferson University, where she served as Chief Cardiology Fellow. She completed fellowship training in Advanced Heart Failure and Transplant Cardiology at the University of California, Los Angeles. Upparapalli is board certified in Internal Medicine, Cardiovascular Disease, Advanced Heart Failure and Transplant Cardiology, Echocardiography, and Nuclear Cardiology.
At UC Irvine, Upparapalli focuses on advanced heart failure, heart transplantation, and mechanical circulatory support including left ventricular assist devices. She has developed expertise in shared care models for advanced heart failure patients in the community, presenting on this topic at multiple symposia including the UCLA Heart Failure Symposium and UCI Essentials in Cardiovascular Disease Symposium. Her clinical skills include right heart catheterization, Swan Ganz catheter placement, endomyocardial biopsies, and advanced echocardiography including transesophageal echocardiography. She has contributed to research on heart failure management strategies and pulmonary embolism treatment approaches.
Upparapalli serves on multiple committees within the UCI Division of Cardiology, including the Clinical Competency Committee for the Cardiovascular Disease Fellowship, the Cardiology Program Evaluation Committee, and the Advanced Heart Failure VAD Quality Task Force. She is actively involved in medical education, teaching medical students, residents, and cardiology fellows through daily clinical rounds, didactic lectures, and supervision of journal club presentations. She has served on the planning committee for the UCI Essentials and Advances in Cardiovascular Disease symposium and previously served as ACC Fellow-in-Training Representative and Fellow Representative for Women in Cardiology for the Delaware Chapter.
Return to topEducation
- M.D., American University of the Caribbean, 2015
- B.A. in Integrative Biology, University of California, Berkeley, 2010
Distinctions
- Edmondson Research Fellow, University of Southern California, Keck School of Medicine, 2009
- Resident of the Quarter, Atlanticare Regional Medical Center, 2016
Areas of Expertise
- Advanced Heart Failure Cardiology
- Mechanical Circulatory Support Devices
- Cardiac Transplantation Management
- Echocardiography Interpretation Techniques
- Cardio-Oncology Treatment Updates
- Mitral Annular Calcification
- Community-Based Shared Care Models
Recent Publications
- Shah S, Bharani V, Vongbunyong K, Zargarian E, Upparapalli D, “A caseous report on mitral annular calcification” (opens in new tab), Journal of the American College of Cardiology, vol. 85, no. 12 Suppl, pp. 04954, 2025. Presented at ACC.25, Chicago, IL.
- Verma A, Fonarow GC, Hsu JJ, Jackevicius CA, Mody FV, Nguyen A, Amidi O, Goldberg S, Vetrivel R, Upparapalli D, Theodoropoulos K, Gregorio S, Chang DS, Bostrom K, Althouse AD, Ziaeian B, “DASH-HF Study: A Pragmatic Quality Improvement Randomized Implementation Trial for Patients with Heart Failure with Reduced Ejection Fraction” (opens in new tab), Circulation: Heart Failure, 2023.
- Verma A, Fonarow GC, Hsu JJ, Jackevicius C, Mody FV, Amidi O, Goldberg S, Upparapalli D, Theodoropoulous K, Chang DS, Bostrom K, Althouse AD, Ziaeian B, “The design of the Dashboard Activated Services and Telehealth for Heart Failure (DASH-HF) study: A pragmatic quality improvement randomized implementation trial for patients with heart failure with reduced ejection fraction” (opens in new tab), Contemporary Clinical Trials, vol. 120, pp. 106895, 2022.
- Graif A, Patel KD, Wimmer NJ, Kimbiris G, Grilli CJ, Upparapalli D, Kaneria AR, Leung DA, “Large-Bore Aspiration Thrombectomy versus Catheter-Directed Thrombolysis for Acute Pulmonary Embolism: A Propensity Score-Matched Comparison” (opens in new tab), Journal of Vascular and Interventional Radiology, vol. 31, no. 12, pp. 2052-2059, 2020.
- Upparapalli D, Vargas J, Tariq H, Dib H, “Here's a Clot, There's a Clot, Everywhere a Clot, Clot: Giant Left Atrial Thrombus with Acute Pulmonary Embolism and Lower Extremity Venous Thrombus – Late Onset Antiphospholipid Syndrome” (opens in new tab), JACC, vol. 73, no. 9_Supplement_1, pp. 2839, 2019.
- Faiek S, Tariq H, Upparapalli D, Bansal A, Sompalli S, “Primary Pulmonary Epithelioid Angiosarcoma: A Rare Case Presentation of Bilateral Pneumothoraces” (opens in new tab), Cureus, vol. 11, no. 12, pp. e6514, 2019.
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Last updated on 3/12/2026.