Deborah Goodman
Adjunct Professor, Department of Epidemiology and Biostatistics, Program in Public Health
Adjunct Professor, Division of Occupational and Environmental Medicine, School of Medicine
Biography
Deborah Goodman, M.D., Ph.D., is Adjunct Professor in the Department of Epidemiology and Biostatistics, Program in Public Health, and the Division of Occupational and Environmental Medicine, School of Medicine, at the University of California, Irvine. She received her Ph.D. in Epidemiology from the University of California, Los Angeles, in 1993 and her M.D. from Rosalind Franklin University/The Chicago Medical School in 1987. Goodman is board certified in Preventive Medicine and has served as a Breast Health Specialist for the WISDOM Study and Athena Breast Health Network at UC Irvine since 2012.
Goodman's research focuses on breast cancer risk assessment and personalized screening, as well as the intersection of environmental exposures, genetics, and chronic disease. She serves as UC Irvine Site Principal Investigator for two major studies: a Patient-Centered Outcomes Research Institute (PCORI)-funded randomized trial comparing personalized versus annual breast cancer screening (2017-2025) and a Department of Defense-funded study examining genetic, epigenetic, and environmental contributions to breast cancer risk assessment (2024-2028). Her earlier work as Principal Investigator on a National Institutes of Health study examined DHEA replacement in healthy older adults, with total funding exceeding $1.6 million.
Goodman has published over 60 peer-reviewed articles examining topics including sex hormones and cardiovascular disease, breast cancer risk factors in multiethnic populations, epigenetic markers of environmental exposures, and participant perspectives on genomic research and data sharing. Her work has appeared in journals such as Circulation, BMJ, Diabetes Care, and the American Journal of Epidemiology. She has contributed to the development of personalized breast cancer prevention decision aids and has been involved in multiple large-scale cohort studies including the Women's Health Initiative and the Athena Breast Health Network.
Return to topEducation
- B.A. in Psychology, University of California, San Diego, 1982
- M.P.H. in Epidemiology, University of California, Los Angeles, 1983
- M.D., Rosalind Franklin University / The Chicago Medical School, 1987
- Ph.D. in Epidemiology, University of California, Los Angeles, 1993
Distinctions
- National Research Service Award, 1990-1993
- Physician Scientist Award, University of California, San Diego, 1993-1995
- Interdisciplinary Team Science Award, ICTS, University of California, Irvine, 2013
Areas of Expertise
- Women's Health Epidemiology
- Cardiovascular Disease Mortality
- Hormone Replacement Therapy
- Postmenopausal Endogenous Sex Hormones
- Personalized Breast Cancer Screening
- Epigenetic Pesticide Exposure Markers
- Genomic Data Sharing Perspectives
Recent Publications
- Esserman L, Fiscalini A, Naeim A, van 't Veer LJ, Kaster A, Scheuner MT, LaCroix AZ, Borowsky AD, Anton-Culver H, Olopade OI, Esserman J, Lancaster R, Madlensky L, Blanco AM, Ross KS, Goodman DL, “Risk-based vs annual breast cancer screening” (opens in new tab), JAMA, 2025.
- Wan JY, Goodman D, Makhnoon S, Norden-Krichmar TM, Wu B, Edwards KL, “Heterogeneity in familial clustering of metabolic syndrome components in the multiethnic GENNID study” (opens in new tab), Obesity, vol. 32, no. 1, pp. 176-186, 2024.
- Wang T, Che M, Huilgol Y, Keane H, Goodman D, “Validation study of risk-reduction activities after personalized breast cancer education tool in the WISDOM Study” (opens in new tab), NPJ Breast Cancer, vol. 10, no. 1, pp. 90, 2024.
- Petruse A, Ryu, Lewis T, Fiscalini AS, Hogarth MA, Wernisch J, Park HL, Fors S, Rocha AN, Johansen L, Sabacan L, Soonavala R, Choy P, Leggat-Barr K, Palmeri M, Hererra M, Goodman S, Van 't Ve Ler, Shieh Y, Madlensky L, et al., “Electronic Health Record Patient Portal (MyChart) Research Study Recruiting Methods and Results: the WISDOM Study” (opens in new tab), Cancer Res, vol. 83, no. 5_Supplement, pp. OT3-18-01, 2023.
- Ziogas A, Feig S, Kirmizi R, Lere C, Alvarez A, Lucia L, Goodman D, “Factors Associated with Longitudinal Changes in Mammographic Density in a Multiethnic Breast Screening Cohort of Postmenopausal Women”, eScholarship, University of California, 2023.
- Lucia RM, Liao X, Huang W-L, Forman D, Kim A, Ziogas A, Norden-Krichmar TM, Goodman D, “Urinary glyphosate and AMPA levels in a cross-sectional study of postmenopausal women: associations with organic eating behavior and dietary intake” (opens in new tab), Int J Hyg Environ Health, vol. 252, pp. 114211, 2023.
- Keane H, Huilgol YD, Shieh Y, Tice J, Belkora J, Sepucha K, Shibley WP, Wang T, Che M, Goodman D, “Development and Pilot of an Online, Personalized Risk Assessment Tool for a Breast Cancer Precision Medicine Trial” (opens in new tab), NPJ Breast Cancer, vol. 7, no. 1, pp. 78, 2021.
- Wan JY, Goodman DL, Willems EL, Freedland A, Norden-Krichmar TM, Santorico SA, Edwards KL, “Genome-wide association analysis of metabolic syndrome quantitative traits in the GENNID multiethnic family study”, Diabetes & Metabolic Syndrome, vol. 13, no. 1, pp. 59, 2021.
Most Cited Publications
- Barrett-Connor E, Goodman-Gruen D, Patay B, “Endogenous sex hormones and cognitive function in older men” (opens in new tab), Journal of Clinical Endocrinology and Metabolism, vol. 84, pp. 3681-3685, 1999.
- Castillo EM, Goodman-Gruen D, Kritz-Silverstein D, Morton DJ, Wingard DL, Barrett-Connor E, “Sarcopenia in elderly men and women: The Rancho Bernardo study” (opens in new tab), American Journal of Preventive Medicine, vol. 25, no. 3, pp. 226-31, 2003.
- Goodman-Gruen D, Barrett-Connor E, “The epidemiology of insulin-like growth factor-I in elderly men and women: The Rancho Bernardo Study” (opens in new tab), American Journal of Epidemiology, vol. 145, pp. 970-976, 1997.
- Goodman-Gruen D, Kritz-Silverstein D, “Usual dietary isoflavones intake and cardiovascular disease risk factors in postmenopausal women” (opens in new tab), Journal of Nutrition, vol. 131, no. 4, pp. 1202-6, 2001.
- Goodman-Gruen D, Barrett-Connor E, “Sex differences in the association of endogenous sex hormone levels and glucose tolerance status in older adult men and women” (opens in new tab), Diabetes Care, vol. 23, pp. 912-918, 2000.
- Promislow JHE, Goodman-Gruen D, Slymen DJ, Barrett-Connor Elizabeth, “Protein Consumption and Bone Mineral Density in the Elderly: The Rancho Bernardo Study” (opens in new tab), American Journal of Epidemiology, vol. 155, pp. 636-44, 2002.
- Barrett-Connor E, Goodman-Gruen D, “A prospective study of endogenous sex hormones and fatal cardiovascular disease in postmenopausal women” (opens in new tab), BMJ, vol. 311, pp. 1193-1196, 1995.
- Barrett-Connor E, Goodman-Gruen D, “The Epidemiology of DHEAS and cardiovascular disease” (opens in new tab), Annals of the New York Academy of Sciences, vol. 774, pp. 259-70, 1996.
- Barrett-Connor E, Goodman-Gruen D, “Dehydroepiandrosterone sulfate does not predict cardiovascular death in postmenopausal women: The Rancho Bernardo Study” (opens in new tab), Circulation, vol. 91, pp. 1757-1760, 1995.
Contact Information
Email: goodmand@uci.edu
Address: 3400 Susan & Henry Samueli College of Health Sciences
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Last updated on 4/28/2026.