Madushka Yohan De Zoysa
Biography
Madushka Yohan De Zoysa, MD, is a Health Sciences Assistant Clinical Professor in the Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology at the University of California, Irvine. De Zoysa received a Doctor of Medicine from the University of Southern California Keck School of Medicine and completed a residency in Obstetrics and Gynecology at LAC+USC Medical Center, followed by a fellowship in Maternal Fetal Medicine at the University of California, Irvine. De Zoysa also completed a fellowship in Fetal Surgery at Cincinnati Children's Hospital Medical Center in the Department of Pediatric Surgery, Maternal Fetal Therapy Division.
De Zoysa's clinical and research focus centers on maternal fetal medicine and fetal interventions, with particular expertise in complex fetal conditions and surgical procedures. De Zoysa has published research on twin-twin transfusion syndrome, examining membrane separation and perinatal outcomes after laser treatment, as well as technical aspects of placental laser surgery. Additional research contributions include work on magnesium sulfate dosing in obstetric patients and cardiovascular disease screening in pregnancy.
De Zoysa serves as Medical Director of Community Outreach and Operations at the Fetal Care Center of Southern California at Children's Hospital of Orange County. De Zoysa is a Fellow of The American College of Obstetricians and Gynecologists and a member of the Society for Maternal-Fetal Medicine. During residency, De Zoysa served as Education Chief Resident at LAC+USC Medical Center.
Return to topEducation
- B.S. in Neuroscience, University of California, Los Angeles, 2011
- M.D., University of Southern California, Keck School of Medicine, 2016
Distinctions
- MacKenzie Primary Care Scholarship, 2014-2015
- Excellence in Medical Student Teaching Award, 2017
- Walker Trust Academic Merit Scholarship, 2014
Areas of Expertise
- Maternal Fetal Medicine
- Twin-Twin Transfusion Syndrome
- Hypertensive Disorders of Pregnancy
- Magnesium Sulfate Dosing
- Fetal Surgical Interventions
- Nonimmune Hydrops Fetalis
- Spontaneous Coronary Artery Dissection
Recent Publications
- Mazza GR, Rau AR, De Zoysa MY, “A Novel Case of NOTCH1 Variant and Nonimmune Hydrops Fetalis: A Case Report” (opens in new tab), Case Rep Genet, vol. 2025, pp. 6865742, 2025.
- De Zoysa MY, Westermann M, Yang T, Chung JH, “The Effect of Body Mass Index on Post-Bolus Magnesium Levels in the Obstetric Patient” (opens in new tab), Am J Perinatol, vol. 41, no. 6, pp. 677-683, 2024.
- Nguyen Pham AB, De Zoysa MY, Ghoshhajra BB, Scott NS, Hameed AB, “Bicoastal Spontaneous Coronary Artery Dissection: A Therapeutic Dilemma” (opens in new tab), AJP Rep, vol. 14, no. 1, pp. e34-e39, 2024.
- De Zoysa MY, Brock CO, Bergh EP, Johnson A, Hernandez-Andrade E, Nobles A, Papanna RM, “Quincke versus diamond-tip needles for entry in placental laser surgery for twin-to-twin transfusion syndrome” (opens in new tab), Fetal Diagn Ther, 2023.
- Chambers ME, De Zoysa MY, Hameed AB, “Screening for cardiovascular disease in pregnancy: is there a need?” (opens in new tab), J Cardiovasc Dev Dis, vol. 9, no. 3, pp. 89, 2022.
- De Zoysa MY, Chon A, Korst L, Llanes A, Chmait R, “Membrane separation and perinatal outcomes after laser treatment for twin-twin transfusion syndrome” (opens in new tab), Fetal Diagn Ther, vol. 47, no. 4, pp. 307-314, 2020.
- Blake E, De Zoysa MY, Morocco E, Kaiser S, Kodama M, Grubbs B, Matsuo K, “Teenage pregnancy complicated by primary invasive ovarian cancer: association for oncologic outcome” (opens in new tab), J Gynecol Oncol, vol. 29, no. 5, pp. e79, 2018.
- De Zoysa MY, Nakamaru N, Kaiser S, Ciccone M, Muderspach L, Matsuo K, “Successful resuscitation after cardiac arrest secondary to carboplatin infusion: A case report” (opens in new tab), Gynecol Oncol Rep, vol. 23, pp. 7-9, 2018.
- Machida H, De Zoysa MY, Takiuchi T, Hom MS, Tierney KE, Matsuo K, “Significance of monocyte counts at recurrence on survival outcome of women with endometrial cancer” (opens in new tab), Int J Gynecol Cancer, vol. 27, no. 2, pp. 302-310, 2017.
Contact Information
Email: mdezoysa@uci.edu
Phone: (714) 456-5616
Address: 3800 West Chapman Avenue, Suite 3400, Orange, CA 92868
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Last updated on 3/24/2026.