Prabodh Kumar Pandey
Biography
Prabodh Kumar Pandey, Ph.D., is Assistant Researcher in the Department of Radiological Sciences at the University of California, Irvine. He received his Ph.D. in Physics from the Indian Institute of Technology, Kanpur in 2020, where his dissertation focused on reconstruction and characterization algorithms for optoacoustic and fluorescence-optoacoustic tomography. His research centers on radiation-induced acoustic imaging and tomography, with particular emphasis on developing physics-informed AI models and model-based reconstruction algorithms for in vivo dosimetry during cancer radiotherapy.
Pandey is Principal Investigator on an NIH/NCI Research Specialist Award (R50 CA283816, 2024-2029) supporting his work on quantitative in vivo dosimetry for radiotherapy using model-based X-ray-induced acoustic computed tomography. He also serves as Key Personnel on an NIH/NCI R37 grant focused on translating 4D in vivo dosimetry approaches for radiation therapy. His research has contributed to the development of novel imaging modalities including protoacoustic radiography and protoacoustic microscopy, as well as three-dimensional reconstruction methods for radiation-induced acoustic computed tomography.
Pandey has authored or co-authored 27 peer-reviewed journal articles and numerous conference proceedings. His work spans computational modeling, algorithm development, and experimental validation of radiation-induced acoustic imaging techniques for applications in proton, electron, and X-ray based cancer treatment. He has mentored undergraduate research projects at UC Irvine and delivered guest lectures on theranostics with radiation-induced ultrasound emission imaging.
Return to topEducation
- Ph.D. in Physics, Indian Institute of Technology, Kanpur, 2020
- M.Sc. in Physics, Indian Institute of Technology, Kanpur, 2010
Distinctions
- NCI Research Specialist Award, National Cancer Institute, National Institute of Health, 2024-2029
- Best paper award for 'Gradient based, one-step reconstruction for quantitative frequency domain photoacoustic tomography' in International Conference on Optics and Electro-optics (ICOL)-2019, 2019
Areas of Expertise
- Biomedical Imaging and Tomography
- Radiation-Induced Acoustic Dosimetry
- Photoacoustic Signal Processing
- Fluorescence Optical Tomography
- Physics-Informed Neural Networks
- Protoacoustic Microscopy
- Quantitative Dose Map Reconstruction
Recent Publications
- Yan Y., Pandey P.K., Xu Y., Sun L., Abi-Jaoudeh N., Wang Z., Xiang S., “XACT-guided interventional procedures: A feasibility study” (opens in new tab), Medical Physics, vol. 53, 2026.
- Jampu B., Naik N., Gottam O., Kumar Pandey P., Gambhir S., “Fully non-linear blob basis based fluorescence photoacoustic pharmaco-kinetic tomography using non-sequential sensitivity evaluations” (opens in new tab), Physics in Medicine and Biology, vol. 71, 2026.
- Prabodh K. Pandey, Gilberto Gonzalez, Kristina Bjegovic, Leshan Sun, Yong Chen, Liangzhong Xiang, “3D protoacoustic radiography: A proof of principle study” (opens in new tab), Applied Physics Letters, vol. 126, no. 7, 2025.
- Siqi Wang, Prabodh K Pandey, Gerald Lee, Rick JP van Bergen, Leshan Sun, Yifei Xu, Liangzhong Xiang, “X-ray–induced acoustic computed tomography: 3D X-ray absorption imaging from a single view” (opens in new tab), Science Advances, vol. 10, no. 49, pp. eads1584, 2024.
- Leshan Sun, Yifei Xu, Prabodh Kumar Pandey, Liangzhong Xiang, “Combined XA/CT Imaging for Bone Density and Elasticity Evaluation: A Simulation Study” (opens in new tab), IEEE Transactions on Radiation and Plasma Medical Sciences, vol. 9, no. 6, pp. 815, 2024.
- Prabodh K. Pandey, Kristina Bjegovic, Gilberto Gonzalez, Liangzhong Xiang, “Resolution limits for radiation-induced acoustic imaging for in vivo radiation dosimetry” (opens in new tab), Physics in Medicine and Biology, vol. 69, no. 16, pp. 165022, 2024.
- Kristina Bjegovic, Leshan Sun, Prabodh K. Pandey, Liangzhong Xiang, “4D in vivo dosimetry for a FLASH electron beam using radiation-induced acoustic imaging” (opens in new tab), Physics in Medicine and Biology, vol. 69, no. 11, pp. 115053, 2024.
- Prabodh K. Pandey, Gilberto Gonzalez, Frederick Cheong, Ce-Belle Chen, Andrew A. Bettiol, Yong Chen, Liangzhong Xiang, “Ionic-resolution protoacoustic microscopy: A feasibility study” (opens in new tab), Applied Physics Letters, vol. 124, no. 5, 2024.
- Kaitlyn Kim, Prabodh K. Pandey, Gilberto Gonzalez, Y. Chen, Liangzhong Xiang, “Simulation Study of Protoacoustics as a Real-time in-line Dosimetry Tool for FLASH Proton Therapy” (opens in new tab), Medical Physics, vol. 51, no. 7, pp. 5070, 2024.
- Rick van Bergen, Leshan Sun, Prabodh Kumar Pandey, Liangzhong Xiang, “Discrete Wavelet Transformation for the Sensitive Detection of Ultrashort Radiation Pulse with Radiation-induced Acoustics” (opens in new tab), IEEE Transactions on Radiation and Plasma Medical Sciences, vol. 8, no. 1, pp. 76, 2024.
- Michelle Simon, Prabodh K. Pandey, Leshan Sun, Liangzhong Xiang, “A graphical user interface (GUI) for model-based radiation-induced acoustic computed tomography” (opens in new tab), Journal of Innovative Optical Health Sciences, vol. 16, no. 1, pp. 2245004-2245004, 2023.
- Chloe J. Chua, Prabodh K. Pandey, Kristen M. Kelly, Liangzhong Xiang, “Feasibility of photoacoustic‐guided ultrasound treatment for port wine stains” (opens in new tab), Lasers in Surgery and Medicine, vol. 55, no. 1, pp. 46-60, 2022.
- Prabodh K Pandey, Hari Om Aggrawal, Siqi Wang, Kaitlyn Kim, An Liu, Liangzhong Xiang, “Ring artifacts removal in X-ray-induced acoustic computed tomography” (opens in new tab), Journal of Innovative Optical Health Sciences, vol. 15, no. 3, pp. 2250017, 2022.
- Omprakash Gottam, Naren Naik, Prabodh K Pandey, Sanjay Gambhir, “RBF level-set based fully-nonlinear fluorescence photoacoustic pharmacokinetic tomography” (opens in new tab), Inverse Problems in Science and Engineering, vol. 29, no. 13, pp. 3227-3260, 2021.
- Ramita Sarkar, Prabodh K Pandey, Satyaki Kundu, Prasanta K Panigrahi, “Exact sub and supersonic pressure wave-fronts in nonlinear thermofluid medium”, Waves in Random and Complex Media, pp. 1-14, 2021.
Most Cited Publications
- Siqi Wang, Vassili Ivanov, Prabodh K Pandey, Liangzhong Xiang, “X-ray-induced acoustic computed tomography (XACT) imaging with single-shot nanosecond x-ray” (opens in new tab), Applied Physics Letters, vol. 119, no. 18, pp. 183702, 2021.
- Leshan Sun, Gilberto Gonzalez, Prabodh K. Pandey, Siqi Wang, Liangzhong Xiang, “Towards Quantitative In Tumor Dosimetry Using X-ray Acoustic Computed Tomography” (opens in new tab), Medical Physics, vol. 50, no. 11, pp. 6895, 2023.
- Prabodh K. Pandey, Siqi Wang, Leshan Sun, Lei Xing, Liangzhong Xiang, “Model-based Three-dimensional X-ray Induced Acoustic Computerized Tomography” (opens in new tab), IEEE Transactions on Radiation and Plasma Medical Sciences, vol. 7, no. 5, pp. 532, 2023.
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Last updated on 6/2/2026.