Sean Valenzuela Arayasirikul
Associate Professor In-Residence, Department of Health, Society and Behavior, Wen Public Health
Co-Director, PhD Program in Health, Society, & Behavior, Wen Public Health
Biography
Sean Arayasirikul, Ph.D. (they/them), is Associate Professor In-Residence and Co-Director of the PhD Programs in Public Health and Health, Society, & Behavior in the Department of Health, Society and Behavior at the Joe C Wen School of Population & Public Health at the University of California, Irvine. They also serve as Co-Director of the Center for Gender and Health Justice at the University of California Global Health Institute and Founding Director of The Legacy Center at Wen Public Health and. The Legacy Center is focused on advancing health equity, justice, and liberation for sexual and gender minoritized (SGM) and all communities through education, research, and community engagement. Dr. Arayasirikul received a Ph.D. in Sociology from the University of California, San Francisco in 2016.
Dr. Arayasirikul's research focuses on digital and mobile health interventions, community-engaged research, and health equity among sexual and gender minoritized communities, particularly transgender women and LGBTQ+ people of color. They are the principal investigator of multiple federally funded studies, including an NIH Director's New Innovator Award (DP2AI164315) supporting "One Ballroom," a national mixed methods longitudinal study examining intersectional HIV stigma and HIV prevention and care among sexual and gender minorities of color in the House and Ballroom Community. They also leads a National Library of Medicine-funded training program (R25LM014575) to advance gender and health justice research and education. Their work has resulted in over 70 peer-reviewed publications with an h-index of 25.
Dr. Arayasirikul was a Fellow of the Robert Wood Johnson Foundation Interdisciplinary Research Leaders Program and has received multiple NIH Loan Repayment Program awards. They created the SHINE Strong Training Program, the first training and mentoring program committed to developing HIV behavioral scientists with expertise in trans population health. Their community-engaged approach to research has been recognized through their governmental appointment on the Orange County HIV Planning Council and as a board member of TruEvolution, and their work has been featured in outlets including The Atlantic, Science, and The Chronicle of Higher Education. Prior to academia, Dr. Arayasirikul has over a decade of frontline public health experience, cross-training substance use and HIV care providers, providing HIV/STI testing and prevention services in non-traditional settings (e.g. mobile clinics, and in situ testing or in community testing), case managing young people living with HIV, creating health promotion programs, and federal service at the Health Resources and Services Administration and the US DHHS Office of Disease Prevention and Health Promotion.
Return to topEducation
- Ph.D. in Sociology, University of California, San Francisco (UCSF), 2016
- B.A. in Asian American Studies, University of California, Los Angeles (UCLA), 2005
Distinctions
- Excellence in Diversity, Equity, and Inclusion Practices, Joe C. Wen School of Population & Public Health, UC Irvine, 2025
- Dean's Honoree for Excellence in Teaching, UC Irvine Wen School of Population & Public Health, UC Irvine Division of Teaching Excellence & Innovation, 2024
- TIME Champion, The Institute for Meaningful Engagement (TIME), Samueli School of Engineering, University of California Irvine, 2023-2026
- Fellow, Interdisciplinary Research Leaders Program, Robert Wood Johnson Foundation, 2021-2024
- Fellow, Inter-Centers for AIDS Research (CFAR) Implementation Science Fellowship, Johns Hopkins University, 2020
- Diversity Scholar, Adolescent Medicine Trials Network for HIV/AIDS Interventions, 2018
- Scholar, LGBTQ Scholars of Color Conference, The Center for Lesbian and Gay Studies (CLAGS), The Graduate Center, City University of New York, 2015
- Dean's Excellence in Teaching Award, University of California, San Francisco, 2014
- Fellow, Minority Fellowship Program, American Sociological Association, 2011
Areas of Expertise
- Sexual and Gender Minoritized Health
- Digital Health Navigation Systems
- Intersectional Stigma and Violence
- Community-Engaged Participatory Methods
- HIV Prevention and Care
- Structural Racism and Geography
- Substance Use Among Youth
Recent Publications
- Shafie A, Salvatore A, Shea R, Yu E, Ozyucel O, Akbar A, Suprasert B, Wilson EC, McFarland W, Taylor K, Arayasirikul S, “Increased vulnerability to psychological distress and suicidal ideation among transgender women with self-reported disabilities in San Francisco, California” (opens in new tab), Preventive Medicine Reports, vol. 54, pp. 103083, 2025.
- Wilson EC, Suprasert B, Trujillo D, Sicro S, Hernandez CJ, Turner CM, McFarland J, Arayasirikul S, “Structural disadvantage and HIV risk – comparing risk factors between trans women's partnerships with cis men and trans women sexual partners” (opens in new tab), BMC Public Health, vol. 25, no. 1, pp. 2813, 2025.
- Arayasirikul S, Turner C, Trujillo D, Maycott J, “Use of and Attitudes Toward Technology among Young People Living with HIV in San Francisco, CA: Cross-sectional Study” (opens in new tab), Jmir Formative Research, vol. 9, pp. e81845, 2025.
- Maycott J, Arayasirikul S, “Racial/Ethnic Inequities in Polysubstance Use Among Online Help-Seeking Sexual and Gender Minoritized People in San Francisco, California 2022-2025: Cross-Sectional Study” (opens in new tab), Jmir Public Health and Surveillance, vol. 11, pp. e82313, 2025.
- Maycott J, Arayasirikul S, “Low Risk Perception of Harm From Substance Use and Sexual Behaviors Among Online Help-Seeking Sexual and Gender Minoritized People in San Francisco, California: Cross-Sectional Survey” (opens in new tab), Jmir Formative Research, vol. 9, pp. e81753, 2025.
- Asbury L., Contestable A., Tran T., Maalouly C., Arayasirikul S., “Joy in the margins: examining narratives of everyday resistance among SGM BIPOC young adults in Orange County” (opens in new tab), BMC Public Health, vol. 25, 2025.
- Wilson EC, Baguso G, Quintana J, Suprasert B, Arayasirikul S, “Detectable viral load associated with unmet mental health and substance use needs among trans women living with HIV in San Francisco, California” (opens in new tab), BMC Women S Health, vol. 24, no. 1, pp. 56, 2024.
- Wilson EC, Turner CM, Dhakal M, Sharma S, Rai A, Lama R, Banik S, Arayasirikul S, “Stigma as a barrier and sex work as a protective factor for HIV testing among trans women in Nepal” (opens in new tab), Plos Global Public Health, vol. 3, no. 3, pp. e0001098, 2023.
- Fisher MR, Turner C, McFarland W, Breslow AS, Wilson EC, Arayasirikul S, “Through a Different Lens: Occupational Health of Sex-Working Young Trans Women” (opens in new tab), Transgender Health, vol. 8, no. 2, pp. 200-206, 2023.
- Wang JC, McFarland W, Arayasirikul S, Wilson EC, “The association between religiosity and resilience among young trans women” (opens in new tab), PLoS One, vol. 18, no. 7, pp. e0263492, 2023.
- Arayasirikul S, Turner C, Trujillo D, Sicro S, Scheer S, McFarland W, Wilson EC, “A global cautionary tale: Discrimination and violence against trans women worsen despite investments in public resources and improvements in health insurance access and utilization of health care” (opens in new tab), International Journal for Equity in Health, vol. 21, no. 1, pp. 32, 2022.
- Arayasirikul S, Turner C, Trujillo D, Maycott J, Wilson EC, “The Dose Response Effects of Digital HIV Care Navigation on Mental Health and Viral Suppression Among Young People Living With HIV: Single-Arm, Prospective Study With a Pre-Post Design” (opens in new tab), Journal of Medical Internet Research, vol. 24, no. 7, pp. e33990, 2022.
- Turner C, Arayasirikul S, Wilson EC, “Disparities in HIV-related risk and socio-economic outcomes among trans women in the sex trade and effects of a targeted, anti-sex-trafficking policy” (opens in new tab), Social Science and Medicine, vol. 270, pp. 113664, 2021.
- Trujillo D, Arayasirikul S, Xie H, Sicro S, Meza J, Bella M, Daza E, Torres F, McFarland W, Wilson EC, “Disparities in Sexually Transmitted Infection Testing and the Need to Strengthen Comprehensive Sexual Health Services for Trans Women” (opens in new tab), Transgender Health, vol. 7, pp. 230-236, 2021.
- Arayasirikul S, Turner CM, Hernandez CJ, Trujillo D, Fisher MR, Wilson EC, “Transphobic Adverse Childhood Experiences as a Determinant of Mental and Sexual Health for Young Trans Women in the San Francisco Bay Area” (opens in new tab), Transgender Health, vol. 7, pp. 552-555, 2021.
- Klemmer C.L., Arayasirikul S., Raymond H.F., “Transphobia-Based Violence, Depression, and Anxiety in Transgender Women: The Role of Body Satisfaction” (opens in new tab), Journal of Interpersonal Violence, vol. 36, pp. 2633-2655, 2021.
Most Cited Publications
- Wilson EC, Chen YH, Arayasirikul S, Raymond HF, McFarland W, “The impact of discrimination on the mental health of trans*female youth and the protective effect of parental support” (opens in new tab), AIDS and Behavior, vol. 20, no. 10, pp. 2203-11, 2016.
- Wilson EC, Chen YH, Arayasirikul S, Wenzel C, Fisher HR, “Connecting the dots: Examining transgender women's utilization of transition-related medical care and the relationship to mental health, substance use and HIV” (opens in new tab), Journal of Urban Health, vol. 92, no. 1, pp. 182-92, 2015.
- DeHaan G, Santos M, Arayasirikul S, Fisher HR, “Non-prescribed hormone use and barriers to care for transgender women in San Francisco” (opens in new tab), LGBT Health, vol. 2, no. 4, pp. 313-323, 2015.
- Wilson EC, Arayasirikul S, Johnson K, “Access to HIV care and support services for African American Transwomen living with HIV” (opens in new tab), International Journal of Transgenderism, vol. 14, no. 4, pp. 182-195, 2014.
- Arayasirikul S, Wilson EC, “Spilling the T on Trans-misogyny and Microaggressions: An Intersectional Oppression and Social Process Among Trans Women” (opens in new tab), Journal of Homosexuality, vol. 66, pp. 1-24, 2018.
- Arayasirikul S, Wilson EC, Fisher HR, “Examining the effects of transphobic discrimination and race on HIV risk among transwomen in San Francisco” (opens in new tab), AIDS and Behavior, vol. 21, pp. 2628-2633, 2017.
- Le V, Arayasirikul S, Chen YH, Jin H, Wilson EC, “Types of social support and parental acceptance among transfemale youth and their impact on mental health, sexual debut, history of sex work and condomless anal intercourse” (opens in new tab), Journal of the International AIDS Society, vol. 19, no. 3 Suppl 2, pp. 20781, 2016.
- Arayasirikul S, Chen YH, Jin H, Wilson EC, “A Web 2.0 and Epidemiology Mash-Up: Using respondent-driven sampling in combination with social network site recruitment to reach young transwomen” (opens in new tab), AIDS and Behavior, vol. 20, no. 6, pp. 1265-74, 2016.
- Arayasirikul S, Pomart A, Raymond HF, Wilson EC, “Unevenness in Health at the Intersection of Gender and Sexuality: Sexual minority disparities in alcohol use and substance use among young transwomen in the San Francisco Bay Area” (opens in new tab), Journal of Homosexuality, vol. 65, pp. 1-14, 2017.
- Wilson EC, Chen YH, Pomart WA, Arayasirikul S, “Awareness, interest and HIV pre-exposure prophylaxis candidacy among young transwomen” (opens in new tab), AIDS Patient Care and Stds, vol. 30, no. 4, pp. 147-50, 2016.
Contact Information
Website: https://sites.uci.edu/legacy/
Email: sean.arayasirikul@uci.edu
Phone: (949) 824-2680
Address: 3228 Susan & Henry Samueli College of Health Sciences
Return to topThis profile was created with the help of AI.
Last updated on 4/2/2026.