Shera Feinstein
Assistant Professor, Department of Radiation Oncology
Biography
Shera Feinstein, M.D., is Assistant Professor in the Department of Radiation Oncology at the UC Irvine Chao Family Comprehensive Cancer Center, where she specializes in genitourinary and breast cancers. She completed her residency in Radiation Oncology at the University of California, Davis in 2024 and received her Doctor of Medicine from the Keck School of Medicine of the University of Southern California in 2019.
Dr. Feinstein's research focuses on radiation oncology immune modulation and oligoprogressive solid tumors. She served as co-investigator on the VALOROUS clinical trial examining ablative therapy in oligoprogressive solid tumors at UC Davis Comprehensive Cancer Center from 2023 to 2024. She currently serves as Site Principal Investigator for two NRG Oncology cooperative group trials, NRG-GU012 and NRG-GU015. Her earlier research as a graduate research fellow at Keck Medicine of USC focused on cutaneous malignancies, particularly lymph node metastasis in cutaneous squamous cell carcinoma.
Dr. Feinstein has authored eight peer-reviewed articles and one book chapter on radiation oncology modalities in metastatic bone disease. She is an authorized user for HDR brachytherapy at UC Irvine Medical Center and holds board certification from the American Board of Radiology in Radiation Oncology. At UC Irvine, she developed the GU Radiation Oncology Didactic Series for the radiation oncology residency program and serves on multiple departmental committees including the Physics Faculty Search Committee and the Radiation Oncology Residency Applicant Interviewer and Ranking Committee.
Return to topEducation
- B.A. in Human Development, University of California, San Diego, 2014
- M.D., Keck School of Medicine of the University of Southern California, 2019
Areas of Expertise
- Radiation Oncology
- Cutaneous Squamous Cell Carcinoma
- Lymph Node Metastasis Patterns
- Sentinel Biopsy Techniques
- Prostate Cancer Radiotherapy
- Oligometastatic Disease Management
- Immune Modulation Strategies
Recent Publications
- Feinstein S, Valicenti R, Zhao X, “Part VI: Radiation Oncology, Chapter 18: Current and Emerging Modalities” (opens in new tab), Metastatic Bone Disease: 2nd Edition, Springer, Cham, 2024.
- Feinstein S, Wang CX, Hunt J, Kim SK, Monjazeb AM, “Advances in Radiotherapy Immune Modulation: From Bench-to-Bedside and Back Again” (opens in new tab), Surg Oncol Clin N Am, vol. 32, no. 3, pp. 617-629, 2023.
- Lobl M, Feinstein S, Lauer S, Sutton A, Wysong A, “Recurrence Status, Perineural Invasion, and Hypothyroidism Are Associated With Lymph Node Metastasis in Cutaneous Squamous Cell Carcinoma: A Case-Control Study” (opens in new tab), Dermatol Surg, vol. 48, no. 4, pp. 381-386, 2022.
- Moon DJ, Higgins S, Feinstein S, Ahadiat O, Sutton A, Wysong A, “Variance of Basal Cell Carcinoma Subtype Reporting by Practice Setting” (opens in new tab), JAMA Dermatol, vol. 155, no. 7, pp. 854-856, 2019.
- Higgins S, Nazemi A, Feinstein S, Chow M, Wysong A, “Clinical Presentations of Melanoma in African Americans, Hispanics, and Asians” (opens in new tab), Dermatol Surg, vol. 45, no. 6, pp. 791-801, 2019.
- Higgins S, Feinstein S, Hawkins M, Cockburn M, Wysong A, “Virtual Reality to Improve the Experience of the Mohs Patient-A Prospective Interventional Study” (opens in new tab), Dermatol Surg, vol. 45, no. 8, pp. 1009-1018, 2019.
- Feinstein S, Higgins S, Ahadiat O, Wysong A, “A Retrospective Cohort Study of Cutaneous Squamous Cell Carcinoma With Lymph Node Metastasis: Risk Factors and Clinical Course” (opens in new tab), Dermatol Surg, vol. 45, no. 6, pp. 772-781, 2019.
- Feinstein S, Sutton A, Wysong A, “Potential Underuse of the Sentinel Lymph Node Biopsy for High-Risk Squamous Cell Carcinoma of the Skin-Reply” (opens in new tab), JAMA Dermatol, vol. 154, no. 8, pp. 973, 2018.
- Suarez J, Wang H, Scott BT, Ling H, Makino A, Swanson E, Brown JH, Suarez JA, Feinstein S, Diaz-Juarez J, Dillmann WH, “In vivo selective expression of thyroid hormone receptor α1 in endothelial cells attenuates myocardial injury in experimental myocardial infarction in mice” (opens in new tab), Am J Physiol Regul Integr Comp Physiol, vol. 307, no. 3, pp. R340-R346, 2014.
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Last updated on 4/8/2026.