Peter Tze-Wei Yu
Biography
Peter Tze-Wei Yu, M.D., M.P.H., F.A.C.S., F.A.A.P., is Section Chair of Pediatric General and Thoracic Surgery and Director of Surgical Research and Surgical Education in the Division of Pediatric Surgery at Children's Hospital of Orange County (CHOC). He also holds appointments as HS Associate Professor in the Departments of Surgery and Pediatrics at the University of California, Irvine School of Medicine. Yu is board-certified in pediatric surgery, surgical critical care, and general surgery, and completed his pediatric surgery fellowship training at The Children's Hospital of Philadelphia and his surgical critical care fellowship at Boston Children's Hospital. He received his M.D. from the University of Missouri School of Medicine and his M.P.H. from The Johns Hopkins Bloomberg School of Public Health.
Yu is the founder of the Fetal Care Center of Southern California, a joint program of CHOC and UCI Health that provides coordinated care for maternal-fetal dyads diagnosed with congenital anomalies. His research focuses on fetal and neonatal surgical conditions—including congenital diaphragmatic hernia, congenital pulmonary airway malformation, and related conditions requiring extracorporeal membrane oxygenation—as well as health disparities in pediatric trauma and access to specialized care. He is Associate Program Director for the CHOC/UCI pediatric surgery fellowship and previously served as Chair of the CHOC Department of Surgery. Yu is an active member of the North American Fetal Therapy Network, serving on its Scientific Review, Publications, Quality/Outcomes, and Advocacy committees, and is a representative to NAFTNet for CHOC and UCI.
Yu is a Fellow of the American College of Surgeons and a Fellow of the American Academy of Pediatrics, and is a member of the American Pediatric Surgical Association, the International Fetal Medicine and Surgery Society, and the Pediatric Trauma Society, among other professional organizations. He serves on the editorial boards of the Journal of Pediatric Surgery Case Reports and Translational Pediatrics, and reviews manuscripts for the Journal of Pediatric Surgery, the Journal of the American College of Surgeons, and the Journal of Trauma and Acute Care Surgery, among other journals. The Fetal Care Center of Southern California has received philanthropic support including a $10,000,000 gift from the Argyros Family Foundation.
Return to topEducation
- B.A. in Psychology, Stanford University, 1999
- M.D., University of Missouri School of Medicine, 2005
- M.P.H., The Johns Hopkins Bloomberg School of Public Health, 2018
Distinctions
- The Louise S. Schnaufer Endowed Fellow in Pediatric Surgery
- Orange County Business Journal 2021 'OC 500', 2021
- Orange County Medical Association Physicians of Excellence, 2022-2025
Areas of Expertise
- Pediatric General and Thoracic Surgery
- Congenital Diaphragmatic Hernia ECMO Outcomes
- Surgical Oncology Signaling Pathways
- Minority Advancement in Academic Medicine
- Fetal Care Access Disparities
- Legal Intervention Youth Mortality
- Congenital Pulmonary Airway Malformation
Recent Publications
- Flyer Z., Giron A., John R., Schomberg J., Carlson A., Dumitr A.M., Wen D., Rohloff A., Lusk J., Yu P.T., “Safety and Efficacy of Ketorolac in the Management of Pain for Postoperative Pediatric General Surgery Patients” (opens in new tab), American Surgeon, vol. 92, pp. 2413-2419, 2026.
- Duehring J.A., Yu P.T., Deihl T.E., Flyer Z., Schomberg J.P., “Placental transcriptome analysis reveals BMI-dependent gene expression profiles in preeclampsia” (opens in new tab), Placenta, vol. 182, pp. 348-353, 2026.
- Giron A., Flyer Z.E., Aziz H., Dumitru A.M., Carlson A., Kohler J.E., Guner Y.S., Yu P.T., “Disparities in Access to Neonatal and Pediatric Extracorporeal Membrane Oxygenation Services in the United States” (opens in new tab), Journal of Surgical Research, vol. 324, pp. 271-280, 2026.
- Heller K., Ochoa B.V., Brierley S.F., Padilla B.E., Alhajjat A., Byrd E., Chao S.D., Clinker C., Diaz-Miron J., Dantes G., Eldredge R.S., Fialkowski E.A., Guner Y., Gurria J.P., Haddadin Z., Highet A., Huerta C.T., Keane O.A., Kelley-Quon L.I., Laje P., et al., “Surgeon annual volume impacts recurrence rates of pediatric inguinal hernia repairs: A multi-institutional study” (opens in new tab), Journal of Pediatric Surgery, vol. 61, 2026.
- Shieh A., Chogle A.S., Yu P.T., “The Great Abdominal Escape: A Delayed Complication after Endoscopy in Pediatric Aerophagia” (opens in new tab), Journal of Emergency Medicine, vol. 85, pp. 1-5, 2026.
- Giron A., Flyer Z.E., Aziz H., Schomberg J., Dumitru A.M., Goodman L.F., Guner Y.S., Perrone E.E., Yu P.T., “Fetal care deserts: Disparities in access to fetal care for birth defects in the United States” (opens in new tab), Journal of Pediatric Surgery, vol. 61, 2026.
- B. Sullivan, J. Schomberg, J. Haduong, S.K. Bose, Y.S. Guner, A. Giron, M. Gholizadeh, P.T. Yu, “Cancer and Trauma Collide: Injury Patterns and Outcomes in the Pediatric Trauma Patient With Cancer” (opens in new tab), The American Surgeon, vol. 91, pp. 961-966, 2025.
- Yu P.T., Giron A., Riley J.S., Adzick N.S., “An illustrated history of fetal surgery for myelomeningocele” (opens in new tab), Translational Pediatrics, vol. 14, pp. 2304-2310, 2025.
- Giron A., Yu P.T., Schomberg J., Aziz H., Flyer Z., Awan S., Ahmad H., Goodman L.F., “Simple vs. Complex Gastroschisis Outcomes: 30-Year Multicenter Review” (opens in new tab), Journal of Pediatric Surgery, vol. 60, 2025.
- Yu PT, Goodman LF, Riley JS, Giron A, Guner YS, Peranteau WH, Schomberg J, “Racial Disparity among Youth Decedents of Legal Intervention Trauma” (opens in new tab), Journal of the American College of Surgeons, vol. 238, no. 2, pp. 226-235, 2024.
- Goodman LF, Yu PT, Awan S, Guner YS, Mohan A, Ge K, Chandy M, Sanchez M, Ehwerhemuepha L, “Congenital Anomalies and Predisposition to Severe COVID-19 Among Pediatric Patients in the United States” (opens in new tab), Pediatric Research, vol. 96, pp. 792-798, 2024.
- A. Giron, J. Schomberg, P.N. Dinh, Z.E. Flyer, L.F. Goodman, Y.S. Guner, P.T. Yu, “EMS Pediatric Trauma Transport: Do Disparities Exist?” (opens in new tab), Journal of Pediatric Surgery, vol. 60, no. 3, pp. 162098, 2024.
- John R, Yu PT, Reyna T, Guner Y, Promprasert P, Hill T, Sayrs L, Stottlemyre RL, Morphew T, Awan S, “Single-center comparison of outcomes between laparoscopic appendectomy and transumbilical laparoscopic assisted appendectomy” (opens in new tab), Journal of Pediatric Surgery, vol. 58, no. 5, pp. 838-843, 2023.
- Riley JS, Schomberg J, Mantha A, Guner YS, Cuevas A, Stephenson CD, Peranteau WH, Yu PT, “A Novel VACTERL Assessment Tool to Facilitate Counseling for Expectant Families” (opens in new tab), Fetal Diagnosis and Therapy, vol. 50, no. 5, pp. 368-375, 2023.
- Gibbs E, Schomberg J, Wallace EL, Bose SK, Yu J, Guner YS, Yu PT, “The role of race in pediatric legal intervention as a cause of injury” (opens in new tab), Journal of Pediatric Surgery, vol. 57, no. 1, pp. 158-167, 2022.
- Stopenski S, Guner YS, Jolley J, Major C, Hatfield T, Ebanks AH, Nguyen DV, Jancelewicz T, Harting MT, Yu PT, “Inborn Versus Outborn Delivery in Neonates with Congenital Diaphragmatic Hernia” (opens in new tab), Journal of Surgical Research, vol. 270, pp. 245-251, 2022.
- Farzaneh CA, Schomberg J, Sullivan BG, Guner YS, Nance ML, Gibbs D, Yu PT, “Development and validation of machine learning models for the prediction of blunt cerebrovascular injury in children” (opens in new tab), Journal of Pediatric Surgery, vol. 57, pp. S0022-3468(21)00781-8, 2021.
Most Cited Publications
- Yu, P.T., Parsa, P.V., Hassanein, O., Rogers, S.O., Chang, D.C., “Minorities Struggle to Advance in Academic Medicine: A 12-Year Review of Diversity at the Highest Levels of America's Teaching Institutions” (opens in new tab), Journal of Surgical Research, vol. 182, no. 2, pp. 212-8, 2013.
- Yu, P.T., Jen, H.C., Rice-Townsend, S., Guner, Y.S., “The role of ECMO in the management of congenital diaphragmatic hernia” (opens in new tab), Seminars in Perinatology, vol. 44, no. 1, pp. 151166, 2020.
- Yu, P.T., Criscuoli, M.L., Jaquish, D., French, R., Maruyama, K., Mose, E., Niessen, S., Hoover, H., Shields, D., Cheresh, D., Cravatt, B., Lowy, A.M., “The RON-Receptor Regulates Pancreatic Cancer Cell Migration Through Phosphorylation-Dependent Breakdown of the Hemidesmosome” (opens in new tab), International Journal of Cancer, vol. 131, no. 8, pp. 1744-54, 2012.
- Jaquish, D., Yu, P.T., Shields, D., Maruyama, K, Niessen, S., Hoover, H., Cheresh, D., Cravatt, B., Lowy, A.M., “IGF1-R Signals Through the RON Receptor to Mediate Pancreatic Cancer Cell Migration” (opens in new tab), Carcinogenesis, vol. 32, no. 8, pp. 1151-6, 2011.
- Yu, P.T., Osen, B.A., Chang, D.C., Talamini, M., “NSQIP Reveals Significant Incidence of Death Following Discharge” (opens in new tab), Journal of Surgical Research, vol. 170, no. 2, pp. e217-24, 2011.
- Guner, Y.S., Nguyen, D.V., Zhang, L., Chen, Y., Harting, M.T., Rycus, P., Barbaro, R., Di Nardo, M., Brogan, T.V., Cleary, J.P., Yu, P.T., “Development and Validation of Extracorporeal Membrane Oxygenation Mortality-Risk Models for Congenital Diaphragmatic Hernia” (opens in new tab), ASAIO Journal, vol. 64, no. 6, pp. 785-794, 2018.
- Delaplain, P.T., Yu, P.T., Ehwerhemuepha, L., Nguyen, D.V., Jancelewicz, T., Stein, J., Harting, M.T., Guner, Y.S., “Predictors of long ECMO runs for congenital diaphragmatic hernia” (opens in new tab), Journal of Pediatric Surgery, vol. 55, no. 6, pp. 993-997, 2020.
- Peterson, C.Y., Osen, B.A., Tran Cao, H.S., Yu, P.T., Chang, D.C., “The Battle of the Sexes: Women Win Out in Gastrointestinal Surgery” (opens in new tab), Journal of Surgical Research, vol. 170, no. 1, pp. e23-8, 2011.
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Last updated on 8/27/2026.